MAP3K6 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MAP3K6 partial ORF ( AAH15914, 225 a.a. - 325 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HFWLHFLLQSCQPFKTACAQGDQCLVLVLEMNKVLLPAKLEVRGTDPVSTVTLSLLEPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQLC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (84); Rat (83)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAP3K6
Entrez GeneID
9064GeneBank Accession#
BC015914Protein Accession#
AAH15914Gene Name
MAP3K6
Gene Alias
ASK2, MAPKKK6, MGC125653, MGC20114
Gene Description
mitogen-activated protein kinase kinase kinase 6
Omim ID
604468Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serine/threonine protein kinase family. The encoded kinase was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. This kinase was found to weakly activate MAPK7, but not MAPK1/ERK or MAPK14. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000005063|apoptosis signal-regulating kinase 2
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Interactome
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