PAPSS1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PAPSS1 partial ORF ( NP_005434, 144 a.a. - 252 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVPENKLHLAKTDAE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.73
Interspecies Antigen Sequence
Mouse (98); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PAPSS1
Entrez GeneID
9061GeneBank Accession#
NM_005443Protein Accession#
NP_005434Gene Name
PAPSS1
Gene Alias
ATPSK1, PAPSS, SK1
Gene Description
3'-phosphoadenosine 5'-phosphosulfate synthase 1
Omim ID
603262Gene Ontology
HyperlinkGene Summary
Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM
Other Designations
3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1
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