PAPSS2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PAPSS2 full-length
Host
Human
Theoretical MW (kDa)
69.5
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PAPSS2 antibody (H00009060-D01P) by Western Blots.
SDS-PAGE Gel
PAPSS2 transfected lysate.
Western Blot
Lane 1: PAPSS2 transfected lysate ( 69.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PAPSS2
Entrez GeneID
9060GeneBank Accession#
NM_004670.3Protein Accession#
NP_004661.2Gene Name
PAPSS2
Gene Alias
ATPSK2, SK2
Gene Description
3'-phosphoadenosine 5'-phosphosulfate synthase 2
Omim ID
603005Gene Ontology
HyperlinkGene Summary
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq
Other Designations
3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2|ATP sulfurylase/APS kinase 2|ATP sulfurylase/adenosine 5'-phosphosulfate kinase|PAPS synthase 2|PAPS synthetase 2|bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2|phosphoadenosine-
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Interactome
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Pathway
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Disease
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