PRC1 monoclonal antibody (M01), clone 3E3-1G1
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of PRC1 expression in transfected 293T cell line by PRC1 monoclonal antibody (M01), clone 3E3-1G1.
Lane 1: PRC1 transfected lysate (Predicted MW: 71.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (93.94 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PRC1.
Immunogen
PRC1 (AAH03138.1, 1 a.a. ~ 620 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEELDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (93.94 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PRC1 expression in transfected 293T cell line by PRC1 monoclonal antibody (M01), clone 3E3-1G1.
Lane 1: PRC1 transfected lysate (Predicted MW: 71.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — PRC1
Entrez GeneID
9055GeneBank Accession#
BC003138Protein Accession#
AAH03138.1Gene Name
PRC1
Gene Alias
ASE1, MGC1671, MGC3669
Gene Description
protein regulator of cytokinesis 1
Omim ID
603484Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is involved in cytokinesis. The encoded protein is at high level during S and G2/M and drop dramatically after cell exit mitosis and enter G1. It is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
anaphase spindle elongation 1 homolog|protein regulating cytokinesis 1
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Interactome
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Disease
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