MAP7 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MAP7 protein.
Immunogen
MAP7 (NP_003971.1, 1 a.a. ~ 749 a.a) full-length human protein.
Sequence
MAELGAGGDGHRGGDGAVRSETAPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGSPSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDVTNSESPEIPLNPILAFDDEGTLGPLPQVDGVQTQQTAEVI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (76)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MAP7 expression in transfected 293T cell line (H00009053-T02) by MAP7 MaxPab polyclonal antibody.
Lane 1: MAP7 transfected lysate(84.10 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MAP7 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — MAP7
Entrez GeneID
9053GeneBank Accession#
NM_003980.3Protein Accession#
NP_003971.1Gene Name
MAP7
Gene Alias
E-MAP-115, EMAP115
Gene Description
microtubule-associated protein 7
Omim ID
604108Gene Ontology
HyperlinkGene Summary
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000017274|dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115))
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Interactome
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Disease
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Publication Reference
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MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon.
Pan X, Cao Y, Stucchi R, Hooikaas PJ, Portegies S, Will L, Martin M, Akhmanova A, Harterink M, Hoogenraad CC.
Cell Reports 2019 Feb; 26(8):1988.
Application:IF, WB, Mouse, Hippocampus neurons, HeLa, HEK 293T, COS-7 cells.
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MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon.
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