PSTPIP1 (Human) Recombinant Protein (Q01)

Catalog # H00009051-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human PSTPIP1 partial ORF ( NP_003969, 148 a.a. - 247 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    CRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDE

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    36.74

    Interspecies Antigen Sequence

    Mouse (87); Rat (86)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — PSTPIP1

    Entrez GeneID

    9051

    GeneBank Accession#

    NM_003978

    Protein Accession#

    NP_003969

    Gene Name

    PSTPIP1

    Gene Alias

    CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP

    Gene Description

    proline-serine-threonine phosphatase interacting protein 1

    Omim ID

    604416 606347

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq

    Other Designations

    CD2 antigen-binding protein 1|CD2 cytoplasmic tail-binding protein|PEST phosphatase-interacting protein 1

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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