PSTPIP1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PSTPIP1 full-length ORF ( AAH08602, 1 a.a. - 416 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
71.5
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PSTPIP1
Entrez GeneID
9051GeneBank Accession#
BC008602Protein Accession#
AAH08602Gene Name
PSTPIP1
Gene Alias
CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Gene Description
proline-serine-threonine phosphatase interacting protein 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq
Other Designations
CD2 antigen-binding protein 1|CD2 cytoplasmic tail-binding protein|PEST phosphatase-interacting protein 1
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Interactome
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Disease
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