PSTPIP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PSTPIP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PSTPIP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PSTPIP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PSTPIP1
Entrez GeneID
9051GeneBank Accession#
PSTPIP1Gene Name
PSTPIP1
Gene Alias
CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Gene Description
proline-serine-threonine phosphatase interacting protein 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq
Other Designations
CD2 antigen-binding protein 1|CD2 cytoplasmic tail-binding protein|PEST phosphatase-interacting protein 1
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Interactome
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Disease
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