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PSTPIP1 rabbit monoclonal antibody

  • Catalog # : H00009051-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PSTPIP1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PSTPIP1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PSTPIP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9051
  • Gene Name:
  • PSTPIP1
  • Gene Alias:
  • CD2BP1,CD2BP1L,CD2BP1S,H-PIP,PAPAS,PSTPIP
  • Gene Description:
  • proline-serine-threonine phosphatase interacting protein 1
  • Gene Summary:
  • The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq
  • Other Designations:
  • CD2 antigen-binding protein 1,CD2 cytoplasmic tail-binding protein,PEST phosphatase-interacting protein 1
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