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Last updated: 2017/7/23

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UBE2M rabbit monoclonal antibody

  • Catalog # : H00009040-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human UBE2M peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human UBE2M is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human UBE2M peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9040
  • GeneBank Accession#:
  • UBE2M
  • Gene Name:
  • UBE2M
  • Gene Alias:
  • UBC-RS2,UBC12,hUbc12
  • Gene Description:
  • ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
  • Gene Summary:
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq
  • Other Designations:
  • nedd8-conjugating enzyme Ubc12,ubiquitin carrier protein M,ubiquitin-conjugating enzyme E2M,ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12),ubiquitin-protein ligase M,yeast UBC12 homolog
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