PKD2L1 monoclonal antibody (M01), clone 4F9
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More Files
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Western Blot (Tissue lysate)
PKD2L1 monoclonal antibody (M01), clone 4F9. Western Blot analysis of PKD2L1 expression in rat brain.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PKD2L1.
Immunogen
PKD2L1 (NP_057196.2, 173 a.a. ~ 272 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYL
Host
Mouse
Reactivity
Human, Rat
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PKD2L1 monoclonal antibody (M01), clone 4F9. Western Blot analysis of PKD2L1 expression in rat brain.Western Blot (Recombinant protein)
ELISA
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Gene Info — PKD2L1
Entrez GeneID
9033GeneBank Accession#
NM_016112Protein Accession#
NP_057196.2Gene Name
PKD2L1
Gene Alias
PCL, PKD2L, PKDL
Gene Description
polycystic kidney disease 2-like 1
Omim ID
604532Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000020283|polycystic kidney disease (polycystin)-like|polycystin-L
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Interactome
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Disease
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Publication Reference
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A novel PKD2L1 C-terminal domain critical for trimerization and channel function.
Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Zeng H, Tang J, Chen XZ.
Scientific Reports 2015 Mar; 5:9460.
Application：SDS-PAGE, WB, Human, Mouse, HEK, HeLa cells, kidney, testis, brain tissues.
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A novel PKD2L1 C-terminal domain critical for trimerization and channel function.
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