SOCS3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SOCS3 full-length ORF ( AAH60858, 1 a.a. - 225 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
50.49
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SOCS3
Entrez GeneID
9021GeneBank Accession#
BC060858Protein Accession#
AAH60858Gene Name
SOCS3
Gene Alias
ATOD4, CIS3, Cish3, MGC71791, SOCS-3, SSI-3, SSI3
Gene Description
suppressor of cytokine signaling 3
Gene Ontology
HyperlinkOther Designations
STAT induced STAT inhibitor 3|cytokine-induced SH2 protein 3
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Interactome
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Pathway
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Disease
- Anorexia Nervosa
- Arthritis
- Asthma
- Atherosclerosis
- Birth Weight
- Body Weight
- Bronchiolitis
- Bulimia
- Diabetes Mellitus
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Publication Reference
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Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α signaling in the rMC-1 cell line.
Jiang Y, Biswas SK, Steinle JJ.
Molecular Vision 2014 Oct; 20:1463.
Application:Treated, Recombinant Protein.
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Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α signaling in the rMC-1 cell line.
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