MAP3K14 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MAP3K14 partial ORF ( AAH35576, 847 a.a. - 947 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ARGRPTDTPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPAAAFSLVTKDGQPVRYDMEVPDSGIDLQCTLAPDGSFAWSWRVKHGQLENRP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (84); Rat (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAP3K14
Entrez GeneID
9020GeneBank Accession#
BC035576Protein Accession#
AAH35576Gene Name
MAP3K14
Gene Alias
FTDCR1B, HS, HSNIK, NIK
Gene Description
mitogen-activated protein kinase kinase kinase 14
Omim ID
604655Gene Ontology
HyperlinkGene Summary
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq
Other Designations
serine/threonine protein-kinase
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Interactome
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Pathway
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Disease
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