TAF1A monoclonal antibody (M01), clone 1F8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TAF1A.
Immunogen
TAF1A (NP_005672, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSDFSEELKGPVTDDEEVETSVLSGAGMHFPWLQTYVETVAIGGKRRKDFAQTTSACLSFIQEALLKHQWQQAAEYMYSYFQTLEDSDSYKRQAAPEIIW
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TAF1A is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — TAF1A
Entrez GeneID
9015GeneBank Accession#
NM_005681Protein Accession#
NP_005672Gene Name
TAF1A
Gene Alias
MGC:17061, RAFI48, SL1, TAFI48
Gene Description
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
Omim ID
604903Gene Ontology
HyperlinkGene Summary
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000035653|OTTHUMP00000035654|SL1, 48kD subunit|TBP-associated factor 1A
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