Immunoprecipitation of TAF1B transfected lysate using anti-TAF1B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TAF1B purified MaxPab mouse polyclonal antibody (B01P) (H00009014-B01P).
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. [provided by RefSeq