TNFSF18 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human TNFSF18 full-length ORF ( NP_005083.1, 1 a.a. - 177 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFLCSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.7
Interspecies Antigen Sequence
Mouse (51)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TNFSF18
Entrez GeneID
8995GeneBank Accession#
NM_005092.2Protein Accession#
NP_005083.1Gene Name
TNFSF18
Gene Alias
AITRL, GITRL, MGC138237, TL6, hGITRL
Gene Description
tumor necrosis factor (ligand) superfamily, member 18
Omim ID
603898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq
Other Designations
AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand
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Interactome
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Disease
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