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PLOD3 Pre-design Chimera RNAi

  • Catalog # : H00008985-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001084
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8985
  • Gene Name:
  • PLOD3
  • Gene Alias:
  • LH3
  • Gene Description:
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
  • Gene Summary:
  • The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq
  • Other Designations:
  • lysine hydroxylase 3,lysyl hydroxylase 3
  • Gene Pathway
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