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WASL 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008976-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-WASL full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 54.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-WASL antibody (H00008976-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008976-T02
    WASL transfected lysate.
    Western Blot
    QC Testing of H00008976-T02
    Lane 1: WASL transfected lysate ( 54.8 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8976
  • Gene Name:
  • WASL
  • Gene Alias:
  • DKFZp779G0847,MGC48327,N-WASP,NWASP
  • Gene Description:
  • Wiskott-Aldrich syndrome-like
  • Gene Summary:
  • The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes. [provided by RefSeq
  • Other Designations:
  • Wiskott-Aldrich syndrome gene-like,Wiskott-Aldrich syndrome gene-like protein,neural Wiskott-Aldrich syndrome protein
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