KYNU polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.88 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant KYNU.
Immunogen
KYNU (NP_003928, 2 a.a. ~ 108 a.a) partial recombinant protein with GST tag.
Sequence
EPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (86)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.88 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — KYNU
Entrez GeneID
8942GeneBank Accession#
NM_003937Protein Accession#
NP_003928Gene Name
KYNU
Gene Alias
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Gene Description
kynureninase (L-kynurenine hydrolase)
Gene Ontology
HyperlinkGene Summary
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
l-kynurenine hydrolase
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Interactome
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Pathway
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Disease
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Publication Reference
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Characterization of the Kynurenine Pathway in Human Neurons.
Guillemin GJ, Cullen KM, Lim CK, Smythe GA, Garner B, Kapoor V, Takikawa O, Brew BJ.
Journal of Neuroscience 2007 Nov; 27(47):12884.
Application：IF, Human, Human neurons, SK-N-SH cells.
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Characterization of the Kynurenine Pathway in Human Neurons.
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