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MBD2 Pre-design Chimera RNAi

  • Catalog # : H00008932-R01
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  • Specification
  • Product Description:
  • Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003927
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8932
  • Gene Name:
  • MBD2
  • Gene Alias:
  • DKFZp586O0821,DMTase,NY-CO-41
  • Gene Description:
  • methyl-CpG binding domain protein 2
  • Gene Summary:
  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. [provided by RefSeq
  • Other Designations:
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