AP1S2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human AP1S2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AP1S2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AP1S2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AP1S2
Entrez GeneID
8905GeneBank Accession#
AP1S2Gene Name
AP1S2
Gene Alias
DC22, MGC:1902, MRX59, SIGMA1B
Gene Description
adaptor-related protein complex 1, sigma 2 subunit
Gene Ontology
HyperlinkGene Summary
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022979|adaptor-related protein complex 1 sigma 2 subunit|clathrin adaptor complex AP1 sigma 1B subunit|clathrin assembly protein complex 1 sigma-1B small chain|clathrin-associated/assembly/adaptor protein small 1-like|golgi adaptor HA1/AP1 ada
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Interactome
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Pathway
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