MCM3AP monoclonal antibody (M01), clone 1H3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MCM3AP.
Immunogen
MCM3AP (AAH13285, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VRVARCCEDVCAHLVDLFLVEEIFQTAKETLQELQCFCKYLQRWREAVTARKKLRRQMRAFPAAPCCVDVSDRLRALAPSAECPIAEENLARGLLDLGHA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MCM3AP is 0.1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to MCM3AP on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — MCM3AP
Entrez GeneID
8888GeneBank Accession#
BC013285Protein Accession#
AAH13285Gene Name
MCM3AP
Gene Alias
FLJ44336, FLJ45306, GANP, KIAA0572, MAP80
Gene Description
minichromosome maintenance complex component 3 associated protein
Omim ID
603294Gene Ontology
HyperlinkGene Summary
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. [provided by RefSeq
Other Designations
MCM3 import protein|MCM3 minichromosome maintenance deficient 3 associated protein|OTTHUMP00000115776|germinal center-associated nuclear protein|minichromosome maintenance deficient 3-associated protein
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