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Last updated: 2016/12/4

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NAE1 rabbit monoclonal antibody

  • Catalog # : H00008883-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NAE1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NAE1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NAE1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8883
  • GeneBank Accession#:
  • NAE1
  • Gene Name:
  • NAE1
  • Gene Alias:
  • A-116A10.1,APPBP1,HPP1,ula-1
  • Gene Description:
  • NEDD8 activating enzyme E1 subunit 1
  • Gene Summary:
  • The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • NEDD8-activating enzyme E1 subunit,amyloid beta precursor protein binding protein 1, 59kDa,amyloid beta precursor protein-binding protein 1, 59kD,amyloid protein-binding protein 1,protooncogene protein 1
  • Gene Pathway
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