Products

Immunoprecipitation-Western Blot

Entrez GeneID

Gene Name

VNN1

Gene Alias

HDLCQ8, MGC116930, MGC116931, MGC116932, MGC116933, Tiff66

Gene Description

vanin 1

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq

Other Designations

OTTHUMP00000017227|Vannin 1|pantetheinase