VNN1 monoclonal antibody (M05), clone 2B10
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of VNN1 transfected lysate using anti-VNN1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with VNN1 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged VNN1 is approximately 0.1ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant VNN1.
Immunogen
VNN1 (NP_004657, 298 a.a. ~ 397 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KLLLSQLDSHPSHSAVVNWTSYASSIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKDLCCHLSYKMSENIPNEVYALGAFDGLHTVEGRYYLQI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (78)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of VNN1 transfected lysate using anti-VNN1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with VNN1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged VNN1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — VNN1
Entrez GeneID
8876GeneBank Accession#
NM_004666Protein Accession#
NP_004657Gene Name
VNN1
Gene Alias
HDLCQ8, MGC116930, MGC116931, MGC116932, MGC116933, Tiff66
Gene Description
vanin 1
Omim ID
603570Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq
Other Designations
OTTHUMP00000017227|Vannin 1|pantetheinase
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