VNN2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
VNN2 transfected lysate.
Western Blot
Lane 1: VNN2 transfected lysate ( 51.48 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-VNN2 full-length
Host
Human
Theoretical MW (kDa)
51.48
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-VNN2 antibody (H00008875-B01) by Western Blots.
SDS-PAGE Gel
VNN2 transfected lysate.
Western Blot
Lane 1: VNN2 transfected lysate ( 51.48 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — VNN2
Entrez GeneID
8875GeneBank Accession#
NM_078488.1Protein Accession#
NP_511043.1Gene Name
VNN2
Gene Alias
FOAP-4, GPI-80
Gene Description
vanin 2
Omim ID
603571Gene Ontology
HyperlinkGene Summary
This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
GPI-80 variant protein 1|GPI-80 variant protein 2|GPI-80 variant protein 3|GPI-80 variant protein 4|Vannin 2|pantetheinase
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Interactome
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Disease
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