VNN2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human VNN2 protein.
Immunogen
VNN2 (NP_511043.1, 1 a.a. ~ 467 a.a) full-length human protein.
Sequence
MNENIDILETAIKQAAEQGARIIVTPEDALYGWKFTRETVFPYLEDIPDPQVNWIPCQDPHRFGHTPVQARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNTEGKLVARYHKYHLYSEPQFNVPEKPELVTFNTAFGRFGIFTCFDIFFYDPGVTLVKDFHVDTILFPTAWMNVLPLLTAIEFHSAWAMGMGVNLLVANTHHVSLNMTGSGIYAPNGPKVYHYDMKTELGKLLLSEVDSHPLSSLAYPTAVNWNAYATTIKPFPVQKNTFRGFISRDGFNFTELFENAGNLTVCQKELCCHLSYRMLQKEENEVYVLGAFTGLHGRRRREYWQVCTMLKCKTTNLTTCGRPVETASTRFEMFSLSGTFGTEYVFPEVLLTEIHLSPGKFEVLKDGRLVNKNGSSGPILTVSLFGRWYTKDSLYSSCGTSNSAITYLLIFILLMIIALQNIVML
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
VNN2 MaxPab polyclonal antibody. Western Blot analysis of VNN2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of VNN2 expression in transfected 293T cell line (H00008875-T01) by VNN2 MaxPab polyclonal antibody.
Lane1:VNN2 transfected lysate(51.37 KDa).
Lane2:Non-transfected lysate.
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Gene Info — VNN2
Entrez GeneID
8875GeneBank Accession#
NM_078488.1Protein Accession#
NP_511043.1Gene Name
VNN2
Gene Alias
FOAP-4, GPI-80
Gene Description
vanin 2
Omim ID
603571Gene Ontology
HyperlinkGene Summary
This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
GPI-80 variant protein 1|GPI-80 variant protein 2|GPI-80 variant protein 3|GPI-80 variant protein 4|Vannin 2|pantetheinase
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Interactome
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Disease
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