ST3GAL5 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ST3GAL5 full-length ORF ( AAH65936.1, 1 a.a. - 390 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPSEYTYVKLRSDCSRPSLQWYTRAQSKMRRPSLLLKDILKCTLLVFGVWILYILKLNYTTEECDMKKMHYVDPDRVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDLSGGIDREF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
71.5
Interspecies Antigen Sequence
Mouse (86); Rat (83)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ST3GAL5
Entrez GeneID
8869GeneBank Accession#
BC065936.1Protein Accession#
AAH65936.1Gene Name
ST3GAL5
Gene Alias
SIAT9, SIATGM3S, ST3GalV
Gene Description
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Gene Ontology
HyperlinkGene Summary
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase|GM3 synthase|OTTHUMP00000160673|alpha 2,3-sialyltransferase V|lactosylceramide alpha-2,3-sialyltransferase|sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase)
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Interactome
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Pathway
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Disease
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