ST3GAL5 monoclonal antibody (M04), clone 8B4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ST3GAL5.
Immunogen
ST3GAL5 (NP_003887, 31 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YTTEECDMKKMHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKFSSKVQT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (83)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.31 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ST3GAL5 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — ST3GAL5
Entrez GeneID
8869GeneBank Accession#
NM_003896Protein Accession#
NP_003887Gene Name
ST3GAL5
Gene Alias
SIAT9, SIATGM3S, ST3GalV
Gene Description
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Gene Ontology
HyperlinkGene Summary
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase|GM3 synthase|OTTHUMP00000160673|alpha 2,3-sialyltransferase V|lactosylceramide alpha-2,3-sialyltransferase|sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase)
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Interactome
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Pathway
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Disease
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