ST3GAL5 rabbit monoclonal antibody
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Specifications
Product Description
Rabbit monoclonal antibody raised against a human ST3GAL5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ST3GAL5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ST3GAL5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ST3GAL5
Entrez GeneID
8869GeneBank Accession#
ST3GAL5Gene Name
ST3GAL5
Gene Alias
SIAT9, SIATGM3S, ST3GalV
Gene Description
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Gene Ontology
HyperlinkGene Summary
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase|GM3 synthase|OTTHUMP00000160673|alpha 2,3-sialyltransferase V|lactosylceramide alpha-2,3-sialyltransferase|sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase)
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