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NR1I2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008856-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-NR1I2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 49.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-NR1I2 antibody (H00008856-D01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008856-T02
    NR1I2 transfected lysate.
    Western Blot
    QC Testing of H00008856-T02
    Lane 1: NR1I2 transfected lysate ( 49.8 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8856
  • Gene Name:
  • NR1I2
  • Gene Alias:
  • Gene Description:
  • nuclear receptor subfamily 1, group I, member 2
  • Gene Summary:
  • This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq
  • Other Designations:
  • orphan nuclear receptor PXR,steroid and xenobiotic receptor
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