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Last updated: 2016/10/23
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NR1I2 purified MaxPab rabbit polyclonal antibody (D01P)MaxPab

  • Catalog # : H00008856-D01P
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human NR1I2 protein.
  • Immunogen:
  • NR1I2 (NP_003880.3, 1 a.a. ~ 434 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of NR1I2 expression in transfected 293T cell line (H00008856-T02) by NR1I2 MaxPab polyclonal antibody.

    Lane 1: NR1I2 transfected lysate(49.80 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8856
  • Gene Name:
  • NR1I2
  • Gene Alias:
  • Gene Description:
  • nuclear receptor subfamily 1, group I, member 2
  • Gene Summary:
  • This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq
  • Other Designations:
  • orphan nuclear receptor PXR,steroid and xenobiotic receptor
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