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PCAF Validated Chimera RNAi

  • Catalog # : H00008850-R01V
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  • Specification
  • Product Description:
  • Homo sapiens p300/CBP-associated factor (PCAF), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003884
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of PCAF over-expressed 293 cell line, cotransfected with PCAF Validated Chimera RNAi ( Cat # H00008850-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with PCAF monoclonal antibody (M02), clone 1H2 (Cat # H00008850-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • PDF DownloadProtocol Download
  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 8850
  • Gene Name:
  • KAT2B
  • Gene Alias:
  • CAF,P,P/CAF,PCAF
  • Gene Description:
  • K(lysine) acetyltransferase 2B
  • Gene Summary:
  • CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq
  • Other Designations:
  • CREBBP-associated factor,p300/CBP-associated factor
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