PCAF (Human) Recombinant Protein (Q02)
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More Files
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Specification
Product Description
Human PCAF partial ORF ( NP_003875, 731 a.a. - 832 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.96
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KAT2B
Entrez GeneID
8850GeneBank Accession#
NM_003884Protein Accession#
NP_003875Gene Name
KAT2B
Gene Alias
CAF, P, P/CAF, PCAF
Gene Description
K(lysine) acetyltransferase 2B
Omim ID
602303Gene Ontology
HyperlinkGene Summary
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq
Other Designations
CREBBP-associated factor|p300/CBP-associated factor
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Interactome
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Pathway
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Disease
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