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WISP2 Pre-design Chimera RNAi

  • Catalog # : H00008839-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens WNT1 inducible signaling pathway protein 2 (WISP2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003881
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8839
  • Gene Name:
  • WISP2
  • Gene Alias:
  • CCN5,CT58,CTGF-L
  • Gene Description:
  • WNT1 inducible signaling pathway protein 2
  • Gene Summary:
  • This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031770,OTTHUMP00000063227,connective tissue growth factor-like protein,wnt-1 signaling pathway protein 2
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