GMPS 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GMPS full-length
Host
Human
Theoretical MW (kDa)
76.34
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GMPS antibody (H00008833-B01) by Western Blots.
SDS-PAGE Gel
GMPS transfected lysate.
Western Blot
Lane 1: GMPS transfected lysate ( 76.34 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GMPS
Entrez GeneID
8833GeneBank Accession#
NM_003875.2Protein Accession#
NP_003866.1Gene Name
GMPS
Gene Alias
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Gene Description
guanine monphosphate synthetase
Gene Ontology
HyperlinkGene Summary
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq
Other Designations
GMP synthase|GMP synthetase|MLL/GMPS fusion protein|glutamine amidotransferase|guanine monophosphate synthetase|guanosine 5'-monophosphate synthase
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Interactome
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Pathway
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Disease
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