IQGAP1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human IQGAP1 partial ORF ( NP_003861, 611 a.a. - 710 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
WQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (90); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IQGAP1
Entrez GeneID
8826GeneBank Accession#
NM_003870Protein Accession#
NP_003861Gene Name
IQGAP1
Gene Alias
HUMORFA01, KIAA0051, SAR1, p195
Gene Description
IQ motif containing GTPase activating protein 1
Omim ID
603379Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq
Other Designations
RasGAP-like with IQ motifs
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Interactome
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Pathway
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