FGF18 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FGF18 full-length
Host
Human
Theoretical MW (kDa)
22.88
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FGF18 antibody (H00008817-B01) by Western Blots.
Western Blot
Lane 1: FGF18 transfected lysate ( 24 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
FGF18 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FGF18
Entrez GeneID
8817GeneBank Accession#
NM_003862Protein Accession#
NP_003853Gene Name
FGF18
Gene Alias
FGF-18, ZFGF5
Gene Description
fibroblast growth factor 18
Omim ID
603726Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq
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