IL18RAP (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human IL18RAP partial ORF ( NP_003844, 20 a.a. - 129 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IL18RAP
Entrez GeneID
8807GeneBank Accession#
NM_003853Protein Accession#
NP_003844Gene Name
IL18RAP
Gene Alias
ACPL, CD218b, CDw218b, IL18RB, MGC120589, MGC120590
Gene Description
interleukin 18 receptor accessory protein
Omim ID
604509Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18. [provided by RefSeq
Other Designations
IL-18 receptor beta|OTTHUMP00000161337|accessory protein-like
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Interactome
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Disease
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