SCEL monoclonal antibody (M01), clone 4B12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SCEL.
Immunogen
SCEL (NP_003834.2, 2 a.a. ~ 97 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (59); Rat (60)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.3 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SCEL is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — SCEL
Entrez GeneID
8796GeneBank Accession#
NM_003843Protein Accession#
NP_003834.2Gene Name
SCEL
Gene Alias
FLJ21667, MGC22531
Gene Description
sciellin
Omim ID
604112Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000018525|OTTHUMP00000018526
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