This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TNFRSF10B transfected lysate using rabbit purified polyclonal anti-TNFRSF10B and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TNFRSF10B.
Antibody pair set content: 1. Antibody pair for IP: rabbit purified polyclonal anti-TNFRSF10B (300 ug) 2. Antibody pair for WB: mouse purified polyclonal anti-TNFRSF10B (50 ug)
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq