TNFRSF10C 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: TNFRSF10C transfected lysate ( 27.4 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
TNFRSF10C transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFRSF10C full-length
Host
Human
Theoretical MW (kDa)
28.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFRSF10C antibody (H00008794-B01) by Western Blots.
Western Blot
Lane 1: TNFRSF10C transfected lysate ( 27.4 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TNFRSF10C transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFRSF10C
Entrez GeneID
8794GeneBank Accession#
NM_003841Protein Accession#
NP_003832Gene Name
TNFRSF10C
Gene Alias
CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID
Gene Description
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Omim ID
603613Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq
Other Designations
TNF related TRAIL receptor|TNF related apoptosis-inducing ligand receptor 3|TRAIL receptor 3|antagonist decoy receptor for TRAIL/Apo-2L|decoy receptor 1|decoy without an intracellular domain|lymphocyte inhibitor of TRAIL|tumor necrosis factor receptor sup
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Interactome
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Disease
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