FPGT purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FPGT protein.
Immunogen
FPGT (NP_003829.2, 1 a.a. ~ 594 a.a) full-length human protein.
Sequence
MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADEKQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSFTILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNPGILVTCADDIELYSIGEFEFIRFDKPGFTALAHPSSLTIGTTHGVFVLDPFDDLKHRDLEYRSCHRFLHKPSIEKMYQFNAVCRPGNFCQQDFAGGDIADLKLDSDYVYTDSLFYMDHKSAKMLLAFYEKIGTLSCEIDAYGDFLQALGPGATVEYTRNTSNVIKEESELVEMRQRIFHLLKGTSLNVVVLNNSKFYHIGTTEEYLFYFTSDNSLKSELGLQSITFSIFPDIPECSGKTSCIIQSILDSRCSVAPGSVVEYSRLGPDVSVGENCIISGSYILTKAALPAHSFVCSLSLKMNRCLKYATMAFGVQDNLKKSVKTLSDIKLLQFFGVCFLSCLDVWNLKVTEELFSGNKTCLSLWTARIFPVCSSLSDSVITSLKMLNAVKNKSAFSLNSYKLLSIEEMLIYKDVEDMITYREQIFLEISLKSSLM
Host
Rabbit
Reactivity
Human, Mouse, Rat
Interspecies Antigen Sequence
Mouse (75); Rat (72)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
FPGT MaxPab rabbit polyclonal antibody. Western Blot analysis of FPGT expression in mouse spleen.Western Blot (Tissue lysate)
FPGT MaxPab rabbit polyclonal antibody. Western Blot analysis of FPGT expression in human colon.Western Blot (Cell lysate)
FPGT MaxPab rabbit polyclonal antibody. Western Blot analysis of FPGT expression in PC-12.Western Blot (Transfected lysate)
Western Blot analysis of FPGT expression in transfected 293T cell line (H00008790-T01) by FPGT MaxPab polyclonal antibody.
Lane 1: FPGT transfected lysate(66.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FPGT
Entrez GeneID
8790GeneBank Accession#
NM_003838.2Protein Accession#
NP_003829.2Gene Name
FPGT
Gene Alias
GFPP
Gene Description
fucose-1-phosphate guanylyltransferase
Omim ID
603609Gene Ontology
HyperlinkGene Summary
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. [provided by RefSeq
Other Designations
GDP-beta-L-fucose pyrophosphorylase|OTTHUMP00000011173|fucose-1-phosphate guanyltransferase
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Interactome
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Pathway
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