TNFRSF18 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: TNFRSF18 transfected lysate ( 26 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
TNFRSF18 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFRSF18 full-length
Host
Human
Theoretical MW (kDa)
26.62
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFRSF18 antibody (H00008784-B01) by Western Blots.
Western Blot
Lane 1: TNFRSF18 transfected lysate ( 26 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TNFRSF18 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFRSF18
Entrez GeneID
8784GeneBank Accession#
NM_004195Protein Accession#
NP_004186Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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