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TNFRSF18 Validated Chimera RNAi

  • Catalog # : H00008784-R01V
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  • Specification
  • Product Description:
  • Homo sapiens tumor necrosis factor receptor superfamily, member 18 (TNFRSF18), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004195
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of TNFRSF18 over-expressed 293 cell line, cotransfected with TNFRSF18 Validated Chimera RNAi ( Cat # H00008784-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with TNFRSF18 monoclonal antibody (M02), clone 1D8 (Cat # H00008784-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • PDF DownloadProtocol Download
  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 8784
  • Gene Name:
  • TNFRSF18
  • Gene Alias:
  • AITR,GITR,GITR-D
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 18
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000001519,OTTHUMP00000001520,OTTHUMP00000001521,TNF receptor superfamily activation-inducible protein,activation-inducible TNFR family receptor,glucocorticoid-induced TNFR-related protein
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