TNFRSF18 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of TNFRSF18 transfected lysate using rabbit polyclonal anti-TNFRSF18 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TNFRSF18.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TNFRSF18 transfected lysate using rabbit polyclonal anti-TNFRSF18 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TNFRSF18.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-TNFRSF18 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-TNFRSF18 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TNFRSF18
Entrez GeneID
8784Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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Interactome
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Pathway
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Disease
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