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Last updated: 2016/12/4

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TNFRSF18 monoclonal antibody (M13), clone 5B2

  • Catalog # : H00008784-M13
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant TNFRSF18.
  • Immunogen:
  • TNFRSF18 (NP_004186.1, 26 a.a. ~ 161 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • QRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAE
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG1 Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8784
  • Gene Name:
  • TNFRSF18
  • Gene Alias:
  • AITR,GITR,GITR-D
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 18
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000001519,OTTHUMP00000001520,OTTHUMP00000001521,TNF receptor superfamily activation-inducible protein,activation-inducible TNFR family receptor,glucocorticoid-induced TNFR-related protein
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