TNFRSF18 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
TNFRSF18 MaxPab rabbit polyclonal antibody. Western Blot analysis of TNFRSF18 expression in mouse spleen.
Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF18 expression in transfected 293T cell line (H00008784-T02) by TNFRSF18 MaxPab polyclonal antibody.
Lane 1: TNFRSF18 transfected lysate(26.00 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TNFRSF18 protein.
Immunogen
TNFRSF18 (NP_004186.1, 1 a.a. ~ 241 a.a) full-length human protein.
Sequence
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TNFRSF18 MaxPab rabbit polyclonal antibody. Western Blot analysis of TNFRSF18 expression in mouse spleen.Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF18 expression in transfected 293T cell line (H00008784-T02) by TNFRSF18 MaxPab polyclonal antibody.
Lane 1: TNFRSF18 transfected lysate(26.00 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TNFRSF18
Entrez GeneID
8784GeneBank Accession#
NM_004195Protein Accession#
NP_004186.1Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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Interactome
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