TNFRSF18 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF18 expression in transfected 293T cell line (H00008784-T01) by TNFRSF18 MaxPab polyclonal antibody.
Lane 1: TNFRSF18 transfected lysate(26.51 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TNFRSF18 protein.
Immunogen
TNFRSF18 (NP_004186, 1 a.a. ~ 241 a.a) full-length human protein.
Sequence
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF18 expression in transfected 293T cell line (H00008784-T01) by TNFRSF18 MaxPab polyclonal antibody.
Lane 1: TNFRSF18 transfected lysate(26.51 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TNFRSF18
Entrez GeneID
8784GeneBank Accession#
NM_004195Protein Accession#
NP_004186Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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Interactome
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Pathway
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Disease
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