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SNAP23 (Human) IP-WB Antibody Pair

  • Catalog # : H00008773-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00008773-PW1
    Immunoprecipitation of SNAP23 transfected lysate using mouse monoclonal anti-SNAP23 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-SNAP23.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: mouse monoclonal anti-SNAP23 (300 ug)
    2. Antibody pair for WB: rabbit polyclonal anti-SNAP23 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8773
  • Gene Name:
  • SNAP23
  • Gene Alias:
  • HsT17016,SNAP23A,SNAP23B
  • Gene Description:
  • synaptosomal-associated protein, 23kDa
  • Gene Summary:
  • Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161263,synaptosomal-associated protein 23
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