TNFRSF6B (Human) Recombinant Protein
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More Files
- More Functions
SDS-PAGE Gel
Western Blot
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Specification
Product Description
Purified TNFRSF6B (AAH17065.1 30 a.a. - 300 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
Transfected Cell Line
Human HEK293T cells
Sequence
VAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
Host
Human
Theoretical MW (kDa)
35.09
Form
Liquid
Preparation Method
Transfection of pSuper-TNFRSF6B plasmid into HEK293T cell, and the expressed protein was purified by Strep-Tactin affinity column.
Purification
Strep-Tactin affinity columns
Concentration
≥ 10 ug/ml
Quality Control Testing
SDS-PAGE and Western Blot
SDS-PAGE Gel
Western Blot
Storage Buffer
100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
SDS-PAGE
Protein Interaction
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Gene Info — TNFRSF6B
Entrez GeneID
8771GeneBank Accession#
BC017065.1Protein Accession#
AAH17065.1Gene Name
TNFRSF6B
Gene Alias
DCR3, DJ583P15.1.1, M68, TR6
Gene Description
tumor necrosis factor receptor superfamily, member 6b, decoy
Omim ID
603361Gene Ontology
HyperlinkGene Summary
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000031583|decoy receptor 3|tumor necrosis factor receptor superfamily, member 6b
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Interactome
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Pathway
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Disease
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